Welcome to Isabella's Pizzaria

640 Main St, Hyannis, MA 02601, United States

General Info

Isabella's Pizzaria at 640 Main St, Hyannis, MA 02601, United States, feels like the kind of restaurant that fits naturally into a relaxed dinner plan. Set along Main Street in Hyannis, this location works well for diners who want a comfortable place to enjoy flavorful dishes, good drinks, and an easygoing atmosphere without making the evening feel too formal.

The menu gives guests several hearty choices, especially for anyone who enjoys Italian-style comfort food with a seafood touch. Octopus is one of the standout dishes, offering something a little more bold for diners who like rich, coastal flavors. Calamari also adds to that seafood-friendly feel, making it a good pick for sharing at the table before moving into something more filling. These small but memorable menu highlights help Isabella's Pizzaria feel suitable for both casual meals and group dining.

For guests who prefer classic, warming dishes, Eggplant Lasagna is a strong option. It brings together familiar layers and a satisfying texture, making it a great choice for dinner when something cozy sounds right. Lasagne also fits that same comforting mood, while Gnocchi adds a softer, more delicate option to the menu. Together, these dishes give the restaurant a nice balance between seafood starters and filling main plates.

Isabella's Pizzaria is also a good match for groups. The setting is casual enough for an easy night out, yet the food choices still feel special enough for a shared meal with friends or family. Dinner service is one of the key reasons to visit, especially for guests looking for a place in Hyannis where the menu has variety and the atmosphere feels welcoming.

The drinks selection adds another layer to the experience. Cocktails are available for those who want something mixed and refreshing, while hard liquor gives guests more options depending on the mood of the night. This makes the restaurant feel like more than just a quick stop for food; it can also work as a relaxed evening spot.

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HOUR OPENING
  • Monday
    Closed
  • Tuesday
    05:00 PM - 09:00 PM
  • Wednesday
    05:00 PM - 09:00 PM
  • Thursday
    05:00 PM - 10:00 PM
  • Friday
    05:00 PM - 10:00 PM
  • Saturday
    05:00 PM - 10:00 PM
  • Sunday
    05:00 PM - 10:00 PM

Isabella's Pizzaria Photos

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What customers say?

“ I would be remiss if I did not give Nonno a review after my wife and I's experience. First, to gather a bit of ethos—and in doing so, explain how I am a snob—I have traveled to 20 countries across Europe, have eaten at Michelin Star restaurants, and have tried diverse cuisine from all corners, and I must say, Nonno not only stands out but is hands-down one of the best restaurants I have ever been to. Between the atmosphere, the amazing host—and his brilliant playlist—the skillful/talented mixologists behind the bar (Tom and Anderson), and the sweetest waitress, we were just stunned by how perfect everything was. It was our first wedding anniversary, and they made it more memorable than it ever would've been with their hospitality and genuine care. Regarding the food, the octopus was exquisite. There are no words to describe the chef’s touch, as they brought perfect balance to the meal in the most unique fashion; so much so that I was genuinely at a loss for words. Again, I have been lucky enough to eat octopus in Malta—where it is a delicacy and the national dish—this dish did not only stay on par with that, but was better than some of those Michelin Star establishments. Between the cocktails, the food, and the service, the experience was brilliant. I will surely be back, as it is now my favorite on this side of the Atlantic, and among the top five restaurants I have ever been to. Well done, Nonno! ”

- Kyle Gravel -

“ Yesterday, I had an incredible experience at Nonno Pizza Cucina & Bar, a cozy and charming restaurant located on Main Street Hyannis. The atmosphere was relaxed and welcoming, and the hosts were very hospitable. The food was absolutely delicious and beautifully presented, with a wide selection of wines and wonderful desserts to top it off. I highly recommend trying the Crispy Octopus and Braised Short Ribs – they were both amazing and melted in my mouth. It was the best meal I've had all summer! The service was outstanding, and the friendly staff, including Fernando and Mariane, made us feel welcome and provided an unforgettable experience. Considering the reasonable prices, it's definitely worth a visit. Overall, I can't wait to come back to Nonno Pizza Cucina & Bar again and again. It's a must-visit spot with amazing food and great service. I highly recommend it to everyone! Risa and Dino Ramos ”

- Risa Manuela Lopes Oliveira-Ramos -

“ Best Italian food on the Cape. Everything tastes like it was cooked by my Nonna. I usually skip Italian food because I am often disappointed. We’ve been twice and will keep going back even though it’s a bit of a drive for us. The service is so attentive - your plates and silverware are always replaced between courses, and the staff is so very friendly and professional. Get two desserts: one for eating there and then take one of their sweet Brazilian pizzas for home. You won’t regret it. ”

- Shayna Ferullo -
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Location & Contact

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information Isabella's Pizzaria:

640 Main St, Hyannis, MA 02601, United States

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